The study reveals why super agents maintain an outstanding memory in their 80 years

Many assume that memory loss and cognitive deterioration are an inevitable part of aging, but new research suggests that this does not have to be the case.

A 25 -year study from the Northwestern University analyzed the brains of the “super agents” to determine what traits they share that they can contribute to their mental resilience.

The “super agers” are defined as people over 80 years of age who show an “outstanding memory performance” that is on par with those who are three younger decades, according to researchers.

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“‘Super ager’ is not a condition, but a term that we define in Northwestern based on a score in a greater memory test of the 80 years,” said main author Sandra Weintraub, professor of psychiatry and behavior sciences and neurology at the News Medical School of the Northwestern University University, said News Digital.

“We were interested in aging memory because the decrease in memory is the most common complaint in older adults. One can be” super “in many ways, and this is just one.”

In the study, the researchers analyzed 79 brains that were donated by super agents and identified some key differences compared to those who “typically age.”

Some of the brains contained amyloid and Tau proteins, which generally accumulate in people with Alzheimer’s disease, while other brains showed no signs of these toxins.

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“Some super agents have very few of these proteins, so for some reason they do not manufacture them,” Weintraub said. “But we found that some super agers brains contained a large number of these proteins, despite maintaining their cognitive health until death.”

This means that there may be different biological routes for the Supercontract: “one resistance and the other resilience,” he said.

“If your relative is forgetful at age 80, it may not be part of aging, but of the disease.”

With the resistance group, they do not make the plates and tangles, said Weintraub. In the resilience group, they do them, but they have no impact on their brains.

While “typically aged” brains show the thinning of the cortex, which is the outer layer of the brain that helps with decision -making, motivation and regulation of emotions, the brains of the super agers did not show this characteristic.

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It was also discovered that super agents had a greater number of “von ecomo neurons”, which are brain cells that control social behavior. The researchers also found that this group had larger “enterinal neurons”, which are essential to feed the memory, according to the launch.

In terms of behavior, it was also discovered that super agents were “highly social” with strong interpersonal relationships, according to study findings.

Challenging assumptions

“There is the common assumption that aging causes a cognitive decline implicitly and that the loss of short -term memory is part of the ‘normal aging,” said News Digital, principal author of Sandra Weintraub, a professor of psychiatry and neurology in Northwestern Medicine.

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“The truth is that, on average, the scores of cognitive tests decrease, but the variance between people within that average period becomes increasing with age,” he continued.

“That means that the loss is not inevitable, and that if its relative is forgetful at age 80, it may not be part of the aging, but of the disease.”

Christopher Weber, Ph.D., senior director of Global Sciences initiatives of the Alzheimer’s Association in Chicago, did not participate in the study, but commented on the “exciting” findings.

“This increases our understanding of people’s brains as they age and gives an idea of what makes some brain changes related to age resiltify or resistant to age -related brain changes,” Weber told News Digital.

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The study shows that super agents have a “more preserved brain structure” that is similar to much younger adults, according to Weber.

“The findings suggest that cognitive deterioration is not an inevitable part of aging, especially for people who have more protective factors that preserve health and cognition of the brain,” he said.

Weber pointed out, however, that the study population of “super aging” is small and is not representative of the real world population.

“They are mainly well educated and white,” he said. “In addition, this group was self -selection in the study. These individuals may be more aware of health or cognitively committed than average older adults.”

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Even so, findings could help scientists create more strategies, and better, to treat and prevent cognitive deterioration, according to Weber.

“The more we know about successful aging, the more opportunities we will have to discover and create interventions to improve resistance and resistance.”

Reduce risk

To help reduce risk factors that affect brain health, Weintraub said: “What is good for your heart is good for your brain.”

“What is good for your heart is good for your brain.”

“We know that adopting certain changes in lifestyle will reduce the risk of a bad result, but it is not guaranteed to eradicate it,” Digital News told News.

“That said, eat well, sleep well, exercise, socialize and value social relationships, treat any condition that you can treat and stay away from harmful substances.”

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The study was supported by the Disease Research Center of Northwest Alzheimer and the National Institute on Aging of National Health Institutes.

The findings were published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.