Four anti-aging approaches revealed in 2025 that can help Americans live longer
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On average, Americans want to live to age 91, according to a recent Pew Research survey, a goal that has spurred attention on practices that increase longevity.
More than 60% of American adults use supplements and most prioritize long-term health and wellness behaviors as part of an anti-aging approach, research has shown.
In 2025, researchers revealed the following anti-aging discoveries that may help you live a longer life.
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1. Vitamin D could slow the aging process
A study by researchers at Mass General Brigham and the Medical College of Georgia found that taking vitamin D supplements can protect against biological aging.
Research published in The American Journal of Clinical Nutrition in May 2025 found that daily supplementation with vitamin D3 can reduce biological wear and tear equivalent to nearly three years of aging.

Vitamin D3 supplementation can reduce biological wear and tear equivalent to almost three years of aging, research has shown. (iStock)
Three months later, Harvard researchers confirmed this correlation with their own study published in the same journal.
Daily vitamin D3 supplementation was found to prevent the shortening of telomeres, the protective ends of chromosome chains, which is a hallmark of aging.
2. Meditation practices can increase longevity
An April 2025 study by Maharishi International University (MIU), the University of Siegen, and the Uniformed Services University of the Health Sciences found that transcendental meditation can significantly relieve stress and slow aging.
Long-term meditation practice involves silently repeating a mantra in your head to achieve deep relaxation.
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The study, published in the journal Biomolecules, found that participants who practiced transcendental meditation had lower expression of genes associated with inflammation and aging.
“These results support other studies indicating that the transcendental meditation technique can reverse or eliminate the lasting effects of stress,” co-author Kenneth Walton, a principal investigator at MIU, previously told News Digital. “The long-lasting effects of stress are now recognized as causing or contributing to all diseases and disorders.”

Those who practiced transcendental mediation had lower expression of genes associated with aging. (iStock)
3. GLP-1 is related to reduced mortality
A September 2025 study found that GLP-1 drugs, which are designed for diabetes and weight loss, could significantly reduce Americans’ mortality.
Researchers at Swiss Re, a reinsurance company in Zurich, Switzerland, estimated that GLP-1 drugs could lead to a 6.4% reduction in all-cause mortality in the US by 2045. In the UK, a mortality reduction of more than 5% was projected over the same 20 years.
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Obesity is a factor that has “stalled progress in life expectancy,” as it is linked to 70% of the leading causes of death in high-income countries, according to researchers.
4. Creativity and socialization could prolong life
In October 2025, several researches investigated the impact of social engagement on longevity.
A study published in the journal Brain, Behavior and Immunity found that social relationships can slow cellular aging.

A September 2025 study found that GLP-1 drugs could significantly reduce Americans’ mortality. (iStock)
Researchers at Cornell University explored the long-term benefits of social connections on biological aging.
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“We found that strong social ties can literally slow down the biological aging process,” the study’s lead author, Anthony Ong, previously said in an interview with News Digital. “Strong social bonds appear to work in the background for many years, building a more resilient body by reducing chronic low-grade inflammation that is a key driver of accelerated aging.”

Social connection is an important factor in prolonging longevity, research has shown. (iStock)
The same month, a similar study was published revealing that creative activities such as music, dance, painting and even certain video games can help keep the brain biologically younger.
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Researchers from 13 countries, including teams from Trinity College Dublin in Ireland and SWPS University in Poland, analyzed brain data from more than 1,400 adults of all ages around the world. Those who regularly engaged in creative hobbies had brain patterns that appeared younger than their actual age.
Even short bursts of creative activity, such as a few weeks of playing strategy video games, had notable benefits.
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News Digital’s Derdre Bardolf and Melissa Rudy contributed reporting.
Angelica Stabile is a lifestyle reporter for News Digital.


