A common murderer is to endanger Americans: pandemic in sight
Five years after the world hyperfoco began in Covid-19, some are worried about the next pandemic, whether it can be caused by the flu, the avian flu or other pathogen.
They are overlooked too easily the viruses not of influenza, non -or bacterial viruses that are flourishing and propagated without control, both in the US. UU. And throughout the world. While they may not cause the next pandemic, they cause a lot of illness and death.
One of those bacteria is Streptococcus Group A, an old enemy that colonizes the throat and tonsils of about 20% of American children, according to Dr. Joshua Osowicki, team leader and senior research member at the Murdoch Child Research Institute in Melbourne, Australia.
CDC warns about the increase in the invasive strain of the streptococcal throat in the US.
This problematic bacterial tension is easily treated with penicillin medications when it causes a clinical infection, OsoWicki told News Digital in an interview in the camera. (See the video at the top of this article).
But the problem, he said, is that because the bacteria can be housed, the diagnosis is not always found early.
Streptococcus group bacteria has been increasing in the world, doctors warn. (Istock)
Scarlatin and rheumatic fever/rheumatic heart disease can be the result of recurrent or unrelated streptococcus, and are increasing again in areas without adequate medical care, including parts of the US. UU.
“Rheumatic heart disease is a chronic non -infectious disease that occurs after unreasonable group streptococcal infections, and almost surely after multiple streptococcal infections based on unreasonable groups,” OsoWicki said.
Infections of the throat of streptocions have shot over the top prior to CO-COVID, says the report: “We have lost the cases”
His research reveals that the prevalence of an invasive version that threatens the life of the Strep A group, which may include deep skin infections, sepsis, meningitis and mortal pneumonia, is increasing in the world.
Aggressive skin infections, which are associated with the use of intravenous drugs, can lead to the need for repeated surgeries, together with antibiotics.
A potentially deadly invasive version of the Strep A group can include deep rooted cutaneous infections, sepsis, meningitis and mortal pneumonia. (Istock)
In the United States, there have been more than twice the annual incidents of Group A Invasive Group in 10 states, which affects about 35 million Americans between 2013 and 2022, with 21,000 cases and approximately 2,000 deaths, according to Oshowicki.
“In many ways, it is a pandemic in sight,” he said about Strep Group A, and added that about one billion people probably experience a symptomatic disease of bacteria every year.
“Actually does its damage in severe and potentially fatal cases before the patient receives antibiotics.”
The important thing with the Strep Group A, according to the doctor, is that the resistance to antibiotics is not the main problem.
“The murderous penicillin in a reliable way, and it has been since 1941 when penicillin was introduced,” OsoWicki said.
Strep colonizes the throat and tonsils of about 20% of American children, according to the researcher. (Istock)
“The point is that it actually does its damage in severe and potentially fatal cases before the patient receives antibiotics. There is a period in which it is too difficult to diagnose and the treatment is too late.”
In those cases, he said, patients need ICU, surgery and “the most intensive treatment we have to offer.”
Among patients over 65, a quarter of them will die with this form of disease, according to OsoWicki.
Need for a vaccine
There is currently no vaccine for Strep Group.
While the most common streptococcal throat and minor skin infections is “less terrifying”, OsoWicki warned about the dangers of overlooking the most invasive version of the disease.
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“Sometimes we look the other way of the infections that threaten the life we fight to prevent, diagnose and treat, (until) these become the cases of first -end sepsis that are seen in the newspaper many weeks of the year,” he said.
“These are cases of holding of headlines. They are cases like Rory Stauunton in New York, whose tragic death (in 2012 of sepsis) really triggered the mandates of the state census in the United States”
There are up to 10 different group streptocent vaccines in development, ranging from completely preclinical vaccines that have never seen a person to vaccines that have been tested in phase 1 tests. (Istock)
The need for an effective vaccine is clear, both for invasive streptoccocence and for the most common variety. Bending and others in their group are working hard to develop them.
“The current impulse of my research is everything related to the vaccine,” he shared. “We do what are called human challenge essays, where we deliberately infected healthy adult volunteers with group A streptococci, painting it in their tonsils. And we do it very carefully, in a hospital environment.”
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Researchers also provide early antibiotic treatments and collect throat, blood and saliva to study how the human only works and explore ways to stop it.
“The ultimate goal is that it really becomes a high -power platform to establish the efficacy of vaccines,” OsoWicki said.
There are many candidates for vaccine in several stages of development, from the type of attached protein (such as Shiningix or the Novavax Covid vaccine) to the Arnm and other types platform, said the researcher.
“We are working with all vaccine companies that have a candidate for the developing group in development,” he said.
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There are up to 10 different group streptocent vaccines in development, ranging from completely preclinical vaccines that have never seen a person to vaccines that have been tested in phase 1 tests, OsoWicki said.
The objective, the researcher said is “to create a vaccine that the world wants, that the world accepts, that the world says it is safe and will help our children.”
He said he is concerned about the skepticism of vaccines, particularly after Covid pandemic, which can prevent people from trusting emerging science.
Even so, the researcher is excited about the future of streptococcus, a vaccine and others, although he hopes he can take at least five to 10 years before a worthy candidate arrives at the doctors’ offices.
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The new vaccine will go to adults with skin infections, as well as the many millions of children who run the risk of minor and serious diseases.
The goal, said OsoWicki, is “to create a vaccine that the world wants, that the world accepts, that the world says it is safe and that will help our children.”
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Marc Siegel, MD is a medical professor and medical director of Doctor Radio at the Nyu Langone Medical Center. He is the senior medical analyst of News Channel and author of “Covid: The Politics of Fear and the Power of Science”. Follow it on Twitter @drmarcsiegel.