Blood pressure and dementia risk share a surprising link, suggests the study
It is known that hypertension, or high blood pressure, has a direct impact on heart attack and the risk of stroke, but a new study has revealed its surprising link with the health of the brain.
In a great randomized essay, researchers led by the University of Medicine of the First Hospital of China discovered that “intensive blood pressure control” resulted in a risk of reduced 15% dementia among participants and a reduced risk of 16% of cognitive deterioration.
The study included 33,995 people in rural China of 40 years or more who had “non -controlled hypertension.”
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The participants were divided into two groups. One received “habitual attention”, while the other was assigned to “trained non -doctors community health suppliers” who prescribed “antihypertensive medications entitled.”
It is known that hypertension, or high blood pressure, has a direct impact on heart attack and the risk of stroke, but a new study has revealed its surprising link with the health of the brain. (Istock)
For the last group, the medications helped them achieve a systolic blood pressure target of <130 mm Hg and a diastolic blood pressure target of <80 mm Hg, according to the studies of the study in nature medicine.
“The primary result of dementia for all causes was significantly lower in the intervention group than in the usual care group,” the researchers wrote.
They also were less likely to experience “serious adverse events.”
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This was one of the first large -scale controlled effectiveness tests, random and controlled to demonstrate a “significant reduction in dementia by all causes associated with the decrease in blood pressure,” the researchers concluded.
There were some limitations of the study, the article recognized, including the absence of cognitive evaluations of reference and monitoring.
“The primary result of dementia for all causes was significantly lower in the intervention group than in the usual care group,” the researchers wrote. (Istock)
Dr. Bradley Serwer, an interventionist cardiologist and medical director of Vitalsolution, an ingenovis health company that offers cardiovascular and anesthesiology services to hospitals, said that this study presents an “intriguing approach” to address dementia in people with non -controlled hypertension.
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“Unlike studies in the United States, this study used non -doctors to significantly reduce blood pressure in rural China through a blinding method of ‘Cluster’,” said Serwer, based in Ohio, who did not participate in the study, News Digital.
It would be beneficial to include basal cognitive evaluations of patients and identify the prevalence of Alzheimer’s dementia within the communities, a doctor said. (Istock)
“While the study may be subject to scrutiny, it raises a relevant question: how crucial is the modification of cardiovascular risk factors in the development of dementia?”
The primary medications used in the lower blood pressure study were the calcium channel blockers and the angiotensin receptor blockers, Serwer said.
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“These commonly prescribed medications have been independently associated with a reduced risk of dementia, regardless of the magnitude of the reduction of blood pressure they achieve,” he said.
“This raises the possibility that the lower rates of dementia observed can be attributed to other beneficial effects of medicines instead of only the reduction of blood pressure.”
This was one of the first large -scale controlled effectiveness tests, random and controlled to demonstrate a “significant reduction in dementia by all causes associated with the decrease in blood pressure,” the researchers said. (Istock)
To confirm the findings, Serwer said it would be beneficial to include cognitive patient cognitive evaluations and identify the prevalence of Alzheimer’s dementia within the communities.
“The most significant conclusion of this study is the deep importance of addressing blood pressure, cholesterol, smoking and sedentary lifestyles,” said the cardiologist.
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“By prioritizing these factors, we not only intend to prevent heart attacks and stroke, but also strive to improve the quality of general life.”
The study was supported by the National Research and Development Program of the Ministry of Science and Technology of China, the Chinese Society of the Foundation of Cardiology and the Science and Technology Program of the Province of Liaoning, China.
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News Digital contacted researchers to comment.
Melissa Rudy is a senior health editor and a member of the lifestyle in News Digital. The advice of history can be sent to melissa.rudy@News.com.